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Magnesium supplement in pregnancy-induced hypertension. A clinicopathological study.
Plain-language guide to PMID 2282207 (1990): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in 18 women.
Key Facts
- PMID
- 2282207
- Journal
- APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
- Year
- 1990
- Study type
- Randomized Controlled Trial
- Authors
- Rudnicki M et al. (5 authors)
- DOI
- 10.1111/j.1699-0463.1990.tb05043.x
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in this randomized controlled trial publication.
The placenta and the umbilical cord obtained from 18 women with pregnancy-induced hypertension were investigated by light microscopy.
Who Took Part
According to the abstract, 18 women were involved.
By PubMed's age tags, the people studied were adults, women only.
The study was performed as a double-blind randomized controlled study in which 11 women were allocated to magnesium and 7 to placebo treatment.
How the Study Was Run
The design is described as randomized, double-blind and placebo-controlled.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
Blinding on both sides kept the women and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.
Some women received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.
What Was Measured
Topics PubMed links to this paper include Blood Pressure, Embryonic and Fetal Development, Endothelium, Vascular, Hypertension, Magnesium, Microscopy, Electron and Placenta.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in 18 women.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
The publication is from 1990 (APMIS : acta pathologica, microbiologica, et immunologica Scandinavica), a journal based in Denmark.
More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.
Our Notes on the Compounds
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.