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Insulin degludec/insulin aspart administered once daily at any meal, with insulin aspart at other meals versus a standard basal-bolus regimen in patients with type 1 diabetes: a 26-week, phase 3, randomized, open-label, treat-to-target trial

Plain-language guide to PMID 22933438 (2012): parallel-group randomized controlled trial study of Insulin Aspart.

Key Facts

PMID
22933438
Journal
Diabetes care
Year
2012
Study type
Randomized Controlled Trial
Authors
Hirsch IB et al. (9 authors)
DOI
10.2337/dc11-2503
Registered trial
NCT00978627

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Insulin Aspart, published as a randomized controlled trial.

How the Study Was Run

The design is described as randomized and parallel-group.

The participants were allocated by chance, so the Insulin Aspart group and the comparison group should start out alike.

The Insulin Aspart group and the comparison group ran side by side rather than switching.

What Was Measured

Topics PubMed links to this paper include Diabetes Mellitus, Type 1, Hypoglycemic Agents, Insulin Aspart, Insulin, Long-Acting and Meals.

What This Means in Plain Language

The paper is a randomized and parallel-group study of Insulin Aspart.

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2012 (Diabetes care), a journal based in United States.

More context: the Insulin Aspart compound page, all human trials.

Our Notes on the Compound

Insulin Aspart: A rapid-acting mealtime insulin analog; brands include NovoLog, NovoRapid and Fiasp.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.