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A 12-week double-blind randomized clinical trial of vitamin D₃ supplementation on body fat mass in healthy overweight and obese women.
Plain-language guide to PMID 22998754 (2012): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 22998754
- Journal
- Nutrition journal
- Year
- 2012
- Study type
- Randomized Controlled Trial
- Authors
- Salehpour A et al. (8 authors)
- DOI
- 10.1186/1475-2891-11-78
- Registered trial
- NCT01344161
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
Vitamin D concentrations are linked to body composition indices, particularly body fat mass.
Relationships between hypovitaminosis D and obesity, described by both BMI and waist circumference, have been mentioned.
Who Took Part
The age groups tagged for this paper are adults and middle-aged adults, women only.
How the Study Was Run
The design is described as randomized, double-blind, placebo-controlled and parallel-group.
The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.
The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.
Groups ran in parallel: each of the participants stayed in one arm throughout.
Body weight, height, waist, hip, fat mass, 25(OH) D, iPTH, and dietary intakes were measured before and after the intervention.
What Was Measured
The subject headings attached to it are 25-Hydroxyvitamin D 2, Adiposity, Body Mass Index, Calcifediol, Cholecalciferol, Dietary Supplements and Iran.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.
Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2012 (Nutrition journal), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.