High prevalence of vitamin D insufficiency in China: relationship with the levels of parathyroid hormone and markers of bone turnover

What Was Tested

The paper reports a study of Parathyroid Hormone (PTH 1-84), published as a randomized controlled trial.

The objectives were to determine the prevalence of vitamin D insufficiency in Shanghai and to investigate the relationship of 25(OH)D with parathyroid function and bone turnover markers.

Why It Was Studied

There is a lack of large-scale studies on vitamin D status and its relationship to parathyroid hormone (PTH) and bone turnover markers in adults living in Shanghai.

This cross-sectional study involved 649 men and 1939 women aged 20-89 years who were randomly sampled in Shanghai.

Who Took Part

The abstract describes 649 men taking part.

The age groups tagged for this paper are young adults, adults, middle-aged adults, older adults and people over 80, both men and women.

How the Study Was Run

The researchers set it up as a randomized study.

Random assignment meant chance, not the researchers, decided who got Parathyroid Hormone (PTH 1-84) and who got the comparison, which limits bias.

Serum concentrations of 25(OH)D, PTH, albumin, and bone turnover markers were measured.

What Was Measured

The subject headings attached to it are Biomarkers, Bone and Bones, China, Cross-Sectional Studies, Parathyroid Hormone, Prevalence and Vitamin D.

What This Means in Plain Language

The paper is a randomized study of Parathyroid Hormone (PTH 1-84) in 649 men.

With several hundred people or more, it is a fairly large study for this kind of research.

The publication is from 2012 (PloS one), a journal based in United States.

More context: the Parathyroid Hormone (PTH 1-84) compound page, all human trials.