Vitamin D status in neonates undergoing cardiac operations: relationship to cardiopulmonary bypass and association with outcomes.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

To determine the incidence of vitamin D deficiency in neonates with congenital heart disease and whether differences exist by race.

In addition, the researchers determined the effect of cardiopulmonary bypass on vitamin D levels and explored associations between 25-hydroxyvitamin D [25(OH)D] levels and postoperative outcomes.

Who Took Part

PubMed tags the participants as both men and women.

How the Study Was Run

In design terms this was a randomized study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

The researchers performed a secondary analysis of a prospective randomized controlled trial in 70 neonates undergoing cardiac surgery.

The neonates' 25(OH)D levels were measured in the operating room before skin incision (baseline), at the cessation of cardiopulmonary bypass, and at 24 hours postoperatively.

Associations between these levels and clinical outcomes were explored.

Vitamin D deficiency was defined as a 25(OH)D level <20 ng/mL.

What Was Measured

The subject headings attached to it are Cardiac Surgical Procedures, Cardiopulmonary Bypass, Ethnicity, Heart Defects, Congenital, Myocardium, Prevalence and Randomized Controlled Trials as Topic.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2013 (The Journal of pediatrics), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.