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Vitamin D supplementation for nonspecific musculoskeletal pain in non-Western immigrants: a randomized controlled trial.
Plain-language guide to PMID 23149532 (2013): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 6, patients.
Key Facts
- PMID
- 23149532
- Journal
- Annals of family medicine
- Year
- 2013
- Study type
- Randomized Controlled Trial
- Authors
- Schreuder F et al. (3 authors)
- DOI
- 10.1370/afm.1402
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.
Many non-Western immigrants report musculoskeletal pains that are hard to treat.
Who Took Part
According to the abstract, 6, patients were involved.
PubMed indexes the participants as young adults, adults and middle-aged adults, both men and women.
How the Study Was Run
In design terms this was a randomized, placebo-controlled and crossover study.
The patients were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.
Each person switched between Vitamin D, K2, Magnesium and Zinc and the comparison at some point, usually with a gap in between.
The researchers conducted a semi-crossover randomized controlled trial between February 2008 and February 2010 in primary care in 84 non-Western immigrants visiting their general practitioner for nonspecific musculoskeletal pain.
The main outcome was self-assessed change in pain after the first 6 weeks.
What Was Measured
The subject headings attached to it are Dietary Supplements, Emigrants and Immigrants, Musculoskeletal Pain, Pain Measurement, Vitamin D and Vitamin D Deficiency.
What This Means in Plain Language
The paper is a randomized, placebo-controlled and crossover study of Vitamin D, K2, Magnesium and Zinc in 6, patients.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2013 (Annals of family medicine), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.