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Vitamin D status and parathyroid hormone levels in patients with obstructive sleep apnea

Plain-language guide to PMID 23154407 (2013): observational study of Parathyroid Hormone (PTH 1-84) in 826 patients, sleep apnea (obstructive).

Key Facts

PMID
23154407
Journal
Respiration; international review of thoracic diseases
Year
2013
Study type
Observational Study
Authors
Barceló A et al. (11 authors)
DOI
10.1159/000342748

What This Study Did, in Plain Language

What Was Tested

Researchers studied Parathyroid Hormone (PTH 1-84) in the context of sleep apnea (obstructive) in this observational study publication.

Vitamin D insufficiency and high levels of parathyroid hormone (PTH) appear to be emerging risk factors for metabolic syndrome (MS), diabetes and cardiovascular disease, conditions that occur frequently in patients with obstructive sleep apnea syndrome (OSAS).

Who Took Part

The study group was 826 patients.

By PubMed's age tags, the people studied were adults, middle-aged adults and older adults, both men and women.

The occurrence of the MS was analyzed according to the National Cholesterol Education Program Adult Treatment Panel III clinical criteria.

How the Study Was Run

Serum levels of 25(OH)D, PTH, glucose, triglycerides, cholesterol, HDL cholesterol, creatinine and uric acid were determined.

What Was Measured

Vitamin D insufficiency and high levels of parathyroid hormone (PTH) appear to be emerging risk factors for metabolic syndrome (MS), diabetes and cardiovascular disease, conditions that occur frequently in patients with obstructive sleep apnea syndrome (OSAS).

PubMed files the paper under topics including Diabetes Complications, Hypertension, Metabolic Syndrome, Parathyroid Hormone, Prevalence, Sleep Apnea, Obstructive and Spain.

What This Means in Plain Language

This is an observational study of Parathyroid Hormone (PTH 1-84) in 826 patients in people with sleep apnea (obstructive).

With several hundred people or more, it is a fairly large study for this kind of research.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2013 (Respiration; international review of thoracic diseases), a journal based in Switzerland.

More context: the Parathyroid Hormone (PTH 1-84) compound page, Sleep apnea (obstructive) research.

Our Notes on the Compound

Parathyroid Hormone (PTH 1-84): The 84-amino-acid hormone that raises blood calcium; full-length PTH (Natpara) has been used in hypoparathyroidism. Teriparatide is its 1-34 fragment.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.