Effects of zinc supplementation on plasma copper/zinc ratios, oxidative stress, and immunological status in hemodialysis patients.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).

The researchers evaluated the effects of Zn supplementation on abnormal plasma Cu/Zn ratios and clinical outcomes in HD patients.

Who Took Part

The age groups tagged for this paper are middle-aged adults and older adults, both men and women.

Age- and sex-matched healthy individuals served as a control group (n = 38).

A number of clinical parameters were measured before and after the supplementation period.

How the Study Was Run

The researchers set it up as a randomized study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

What Was Measured

The researchers evaluated the effects of Zn supplementation on abnormal plasma Cu/Zn ratios and clinical outcomes in HD patients.

Topics PubMed links to this paper include CD4-Positive T-Lymphocytes, Copper, Dietary Supplements, Inflammation, Oxidative Stress, Renal Dialysis and Superoxide Dismutase.

Author keywords: copper/zinc ratios, hemodialysis patients, immune function and zinc supplement.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).

Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2013 (International journal of medical sciences), a journal based in Australia.

More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.