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Vitamin D supplementation and calcium absorption during caloric restriction: a randomized double-blind trial.

Plain-language guide to PMID 23364004 (2013): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 82 women.

Key Facts

PMID
23364004
Journal
The American journal of clinical nutrition
Year
2013
Study type
Randomized Controlled Trial
Authors
Shapses SA et al. (7 authors)
DOI
10.3945/ajcn.112.044909
Registered trial
NCT00473031

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Who Took Part

According to the abstract, 82 women were involved.

The age groups tagged for this paper are middle-aged adults, women only.

The researchers measured TFCA with the use of dual-stable isotopes, 25(OH)D, parathyroid hormone, estradiol, calcitriol, and urinary calcium at baseline and 6 wk in weight loss and vitamin D(3)-supplementation (WL-D; n = 19), weight maintenance and vitamin D(3)-supplementation (WM-D; n = 20), weight loss and placebo (n = 22), and weight maintenance and placebo (n = 21) groups.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Neither the women nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

Some women received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

What Was Measured

Topics PubMed links to this paper include Body Composition, Calcium, Dietary, Caloric Restriction, Cholecalciferol, Dietary Supplements, Parathyroid Hormone and Regression Analysis.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 82 women.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2013 (The American journal of clinical nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.