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Induction of labor with titrated oral misoprostol solution versus oxytocin in term pregnancy: randomized controlled trial

Plain-language guide to PMID 23412004 (2013): randomized controlled trial study of Oxytocin in 285 women.

Key Facts

PMID
23412004
Journal
Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia
Year
2013
Study type
Randomized Controlled Trial
Authors
Aalami-Harandi R et al. (3 authors)
DOI
10.1590/s0100-72032013000200004

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Oxytocin, published as a randomized controlled trial.

Who Took Part

The study group was 285 women.

By PubMed's age tags, the people studied were adults, women only.

Between 2008 and 2010, a total of 285 term pregnant women whom were candidate for vaginal delivery were assessed for eligibility to enter the study.

Twenty five patients were excluded for different reasons; and 260 included women were randomly assigned to one of the two groups according to the method of treatment, misoprostol or oxytocin.

How the Study Was Run

The researchers set it up as a randomized study.

The women were allocated by chance, so the Oxytocin group and the comparison group should start out alike.

The time from induction to delivery and induction to the beginning of the active phase and successful inductions within 12, 18, and 24 hours were recorded.

The trial is registered at irct.ir, number IRCT2012061910068N1.

What Was Measured

PubMed files the paper under topics including Labor, Induced, Misoprostol, Oxytocics, Oxytocin and Pregnancy Trimester, Third.

What This Means in Plain Language

The paper is a randomized study of Oxytocin in 285 women.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2013 (Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia), a journal based in Brazil.

More context: the Oxytocin compound page, all human trials.

Our Notes on the Compound

Oxytocin: A peptide hormone with established obstetric medical uses and a less settled role in research on behavior, sexual function and appetite.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.