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Effects of weight loss and exercise on apelin serum concentrations and adipose tissue expression in human obesity

Plain-language guide to PMID 23429279 (2013): clinical trial study of Apelin in 740 individuals, fat loss, obesity & body recomposition.

Key Facts

PMID
23429279
Journal
Obesity facts
Year
2013
Study type
Clinical Trial
Authors
Krist J et al. (15 authors)
DOI
10.1159/000348667

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Apelin in the context of fat loss, obesity & body recomposition, published as a clinical trial.

Who Took Part

The study group was 740 individuals.

The age groups tagged for this paper are adults, both men and women.

Apelin serum concentration was measured in 740 individuals in a cross-sectional (n = 629) study including a subgroup (n = 161) for which omental and SC apelin mRNA expression has been analyzed and in three interventions: 12 weeks exercise (n = 60), 6 months calorie-restricted diet (n = 19), 12 months after bariatric surgery (n = 32).

What Was Measured

Topics PubMed links to this paper include Adiposity, Apelin, Apelin Receptors, Bariatric Surgery, Blood Glucose, Body Mass Index and Caloric Restriction.

What This Means in Plain Language

This is a clinical trial of Apelin in 740 individuals in people with fat loss, obesity & body recomposition.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2013 (Obesity facts), a journal based in Switzerland.

More context: the Apelin compound page, Fat loss, obesity & body recomposition research.

Our Notes on the Compound

Apelin: A peptide hormone family that acts on the heart and blood vessels; studied as an infusion in heart and lung research.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.