Aged garlic extract with supplement is associated with increase in brown adipose, decrease in white adipose tissue and predict lack of progression in coronary atherosclerosis.

What Was Tested

This randomized controlled trial looks at Plant Extracts.

The researchers evaluated the effects of AGE-S on change in white (wEAT) and brown (bEAT) epicardial adipose tissue, homocysteine and CAC.

Who Took Part

PubMed indexes the participants as adults, middle-aged adults and older adults, men only.

How the Study Was Run

The researchers set it up as a randomized and placebo-controlled study.

Because people in this Plant Extracts study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

The comparison arm used a placebo, so changes seen with Plant Extracts could be set against what happens without it.

The postcuff deflation temperature-rebound index of vascular function was assessed using a reactive-hyperemia procedure.

Vascular dysfunction was defined according to the tertiles of temperature-rebound at 1 year of follow-up.

What Was Measured

The researchers evaluated the effects of AGE-S on change in white (wEAT) and brown (bEAT) epicardial adipose tissue, homocysteine and CAC.

PubMed files the paper under topics including Adipose Tissue, Brown, Adipose Tissue, White, Atherosclerosis, Coronary Artery Disease, Coronary Vessels, Dietary Supplements and Disease Progression.

Author keywords: Aged garlic extract, Coronary artery calcium, Vascular function and White epicardial adipose tissue.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Plant Extracts.

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2013 (International journal of cardiology), a journal based in Netherlands.

More context: all human trials.