A randomized clinical trial of the efficacy of extended smoking cessation treatment for adolescent smokers

What Was Tested

The paper reports a study of Therapeutic nicotine (patch, non-peptide), published as a randomized controlled trial.

Intention-to-treat logistic regression analysis was used to assess the primary outcome of biologically confirmed (carbon monoxide < 9 ppm) point prevalence abstinence at Week 26 (6-month follow-up from baseline).

Why It Was Studied

Relatively few well-designed smoking cessation studies have been conducted with teen smokers.

Who Took Part

The age groups tagged for this paper are teenagers, both men and women.

Open-label smoking cessation treatment consisted of 10 weeks of school-based, cognitive-behavioral group counseling along with 9 weeks of nicotine replacement (nicotine patch).

How the Study Was Run

The design is described as randomized and open-label.

Random assignment meant chance, not the researchers, decided who got Therapeutic nicotine (patch, non-peptide) and who got the comparison, which limits bias.

Being open-label, the Therapeutic nicotine (patch, non-peptide) study did not mask who received what.

The methods mention a period of 14 weeks.

A total of 141 adolescent smokers in continuation high schools in the San Francisco Bay Area were randomized to either 9 additional group sessions over a 14-week period (extended group) or 4 monthly smoking status calls (nonextended group).

What Was Measured

Topics PubMed links to this paper include Nicotine, Smoking, Smoking Cessation and Smoking Prevention.

What This Means in Plain Language

The paper is a randomized and open-label study of Therapeutic nicotine (patch, non-peptide) over 14 weeks.

The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2013 (Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco), a journal based in England.

More context: the Therapeutic nicotine (patch, non-peptide) compound page.