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Advantages of recombinant follicle-stimulating hormone over human menopausal gonadotropin for ovarian stimulation in intrauterine insemination: a randomized clinical trial in unexplained infertility
Plain-language guide to PMID 23541417 (2013): randomized controlled trial study of HMG (Human Menopausal Gonadotropin).
Key Facts
- PMID
- 23541417
- Journal
- European journal of obstetrics, gynecology, and reproductive biology
- Year
- 2013
- Study type
- Randomized Controlled Trial
- Authors
- Rashidi M et al. (6 authors)
- DOI
- 10.1016/j.ejogrb.2013.03.002
What This Study Did, in Plain Language
What Was Tested
Researchers studied HMG (Human Menopausal Gonadotropin) in this randomized controlled trial publication.
To compare two different gonadotropin preparations, human menopausal gonadotropin (hMG) and recombinant follicle-stimulating hormone (rFSH), combined with clomiphene citrate (CC) in women with unexplained infertility undergoing intrauterine insemination (IUI).
Who Took Part
The age groups tagged for this paper are adults, both men and women.
How the Study Was Run
The design is described as randomized.
Because people in this HMG (Human Menopausal Gonadotropin) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
In this prospective clinical trial, couples prepared for IUI cycles were randomly allocated to two groups either to receive CC and hMG (group A, n=127) or CC and rFSH (group B, n=132) for ovarian stimulation.
Outcomes including rates of clinical pregnancy, miscarriage, OHSS, multiple pregnancy, cancellation, and live birth were compared between groups.
What Was Measured
Topics PubMed links to this paper include Clomiphene, Fertility Agents, Female, Follicle Stimulating Hormone, Infertility, Female, Insemination, Artificial, Homologous, Menotropins and Ovulation Induction.
The authors tagged it with the keywords Human menopausal gonadotropin, Intrauterine insemination, Recombinant follicle-stimulating hormone and Unexplained infertility.
What This Means in Plain Language
The paper is a randomized study of HMG (Human Menopausal Gonadotropin).
Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2013 (European journal of obstetrics, gynecology, and reproductive biology), a journal based in Ireland.
More context: the HMG (Human Menopausal Gonadotropin) compound page, all human trials.
Our Notes on the Compound
HMG (Human Menopausal Gonadotropin): Menotropins: a glycoprotein preparation that supplies follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.