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[Effects of Xingpi Yang'er granule on serum gastrin, plasma motilin, and somatostatin contents in children patients with pneumonia induced diarrhea]

Plain-language guide to PMID 23646465 (2013): randomized controlled trial study of Somatostatin in 120 children.

Key Facts

PMID
23646465
Journal
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
Year
2013
Study type
Randomized Controlled Trial
Authors
Xin-Xin C et al. (2 authors)

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial paper looks at Somatostatin.

To observe the effects of Xingpi Yang'er Granule (XYG) on serum gastrin (GAS), plasma motilin (MOT), and somatostatin (SS) in children patients with pneumonia induced diarrhea.

Who Took Part

According to the abstract, 120 children were involved.

PubMed indexes the participants as infants and young children, both men and women.

Recruited were 120 children inpatients with pneumonia induced diarrhea at the Department of Pediatrics, Liaocheng People's Hospital from June 2011 to June 2012.

They were randomly assigned to two groups, the treatment group and the control group, 60 in each group.

How the Study Was Run

In design terms this was a randomized study.

Random assignment meant chance, not the researchers, decided who got Somatostatin and who got the comparison, which limits bias.

Those in the treatment group were treated with XYG, while those in the control group were treated with Live Combined Bifidobacterium and Lactobacillus Tablets.

Besides, 30 healthy children who received physical examinations at their hospital were recruited as the healthy control group.

What Was Measured

The subject headings attached to it are Diarrhea, Drugs, Chinese Herbal, Gastrins, Motilin, Phytotherapy, Pneumonia and Somatostatin.

What This Means in Plain Language

The paper is a randomized study of Somatostatin in 120 children.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2013 (Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine), a journal based in China.

More context: the Somatostatin compound page, all human trials.

Our Notes on the Compound

Somatostatin: A 14-amino-acid hormone that switches off the release of several other hormones, including growth hormone and insulin.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.