Treatment of glaucomatous patients by means of food supplement to reduce the ocular discomfort: a double blind randomized trial.

What Was Tested

Researchers studied Rutin in this randomized controlled trial publication.

Who Took Part

The study group was 38 patients.

The age groups tagged for this paper are adults, middle-aged adults and older adults.

This double blind, randomized, pilot study was conducted on 38 glaucomatous patients suffering from dry eye induced by long-term use of eye drops preserved with BAK.

How the Study Was Run

The design is described as randomized, double-blind and pilot.

Random assignment meant chance, not the researchers, decided who got Rutin and who got the comparison, which limits bias.

Neither the patients nor the staff measuring them knew who was on Rutin, so expectations could not easily colour the readings.

It is described as a pilot, a small early test of whether a larger Rutin study would be practical.

What Was Measured

Topics PubMed links to this paper include Colforsin, Dietary Supplements, Dry Eye Syndromes, Glaucoma, Riboflavin, Rutin and Thiamine.

What This Means in Plain Language

The paper is a randomized, double-blind and pilot study of Rutin in 38 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 2 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2013 (European review for medical and pharmacological sciences), a journal based in Italy.

More context: all human trials.