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Effect of calcium plus vitamin D supplementation during pregnancy in Brazilian adolescent mothers: a randomized, placebo-controlled trial.
Plain-language guide to PMID 23719547 (2013): single-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 23719547
- Journal
- The American journal of clinical nutrition
- Year
- 2013
- Study type
- Randomized Controlled Trial
- Authors
- Diogenes ME et al. (6 authors)
- DOI
- 10.3945/ajcn.112.056275
- Registered trial
- NCT01732328
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
Pregnancy and lactation in adolescents with habitually low calcium intake may adversely affect maternal bone mass.
Who Took Part
The age groups tagged for this paper are teenagers and young adults, women only.
How the Study Was Run
The design is described as randomized, single-blind and placebo-controlled.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Only one side, usually the participants, was kept unaware of whether Vitamin D, K2, Magnesium and Zinc was given.
A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.
The bone mineral content (BMC), bone area (BA), and bone mineral density (BMD) at the total body, lumbar spine, and hip (total and femoral neck) were evaluated by using dual-energy X-ray absorptiometry at 5 and 20 wk postpartum.
Serum hormones and 25-hydroxyvitamin D [25(OH)D] were measured.
What Was Measured
The subject headings attached to it are Absorptiometry, Photon, Bone Density, Bone and Bones, Brazil, Calcium, Dietary, Cholecalciferol and Dietary Supplements.
What This Means in Plain Language
The paper is a randomized, single-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.
The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2013 (The American journal of clinical nutrition), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.