The effects of nicotine content information on subjective and behavioural responses to nicotine-containing and denicotinized cigarettes.

What Was Tested

This randomized controlled trial looks at Therapeutic nicotine (patch, non-peptide).

The effects of nicotine content information on subjective and behavioural responses to nicotine-containing and denicotinized cigarettes were examined in 30 dependent and 30 nondependent 12-h abstinent smokers.

During each session, participants completed subjective assessments before and after sampling three puffs from the assigned cigarette and were then invited to earn additional cigarette puffs using a computerized progressive ratio task.

Who Took Part

The age groups tagged for this paper are young adults, adults and middle-aged adults, both men and women.

Using the four conditions of a balanced placebo design, participants were given either nicotine-containing cigarettes or denicotinized cigarettes during two laboratory sessions but were told that they received nicotine-containing cigarettes in one session and nicotine-free cigarettes in the other.

How the Study Was Run

The design is described as randomized, single-blind and placebo-controlled.

The participants were allocated by chance, so the Therapeutic nicotine (patch, non-peptide) group and the comparison group should start out alike.

Only one side, usually the participants, was kept unaware of whether Therapeutic nicotine (patch, non-peptide) was given.

A placebo (an inactive look-alike) gave the Therapeutic nicotine (patch, non-peptide) group a baseline to be compared against.

What Was Measured

During each session, participants completed subjective assessments before and after sampling three puffs from the assigned cigarette and were then invited to earn additional cigarette puffs using a computerized progressive ratio task.

The subject headings attached to it are Behavior, Addictive, Motivation, Nicotinic Agonists, Self Administration, Tobacco Use Cessation Devices and Tobacco Use Disorder.

What This Means in Plain Language

The paper is a randomized, single-blind and placebo-controlled study of Therapeutic nicotine (patch, non-peptide).

The publication is from 2013 (Behavioural pharmacology), a journal based in England.

More context: the Therapeutic nicotine (patch, non-peptide) compound page, all human trials.