Acute aerobic exercise differentially alters acylated ghrelin and perceived fullness in normal-weight and obese individuals

What Was Tested

The paper reports a study of Ghrelin, published as a randomized controlled trial.

Therefore, the purpose of this study was to determine whether adiposity [normal-weight (NW) vs. obese (Ob)] influences the effect of exercise and feeding on acylated ghrelin, hunger, and fullness.

Frequent blood samples were taken and analyzed for acylated ghrelin, and a visual analog scale was used to assess perceived hunger and fullness.

Why It Was Studied

Adiposity alters acylated ghrelin concentrations, but it is unknown whether adiposity alters the effect of exercise and feeding on acylated ghrelin responses.

Fourteen NW and 14 Ob individuals completed two trials in a randomized counterbalanced fashion, including a prior exercise trial (EX) and a no exercise trial (NoEX).

Who Took Part

The abstract describes 14 individuals taking part.

By PubMed's age tags, the people studied were adults, both men and women.

How the Study Was Run

The researchers set it up as a randomized study.

Random assignment meant chance, not the researchers, decided who got Ghrelin and who got the comparison, which limits bias.

What Was Measured

The subject headings attached to it are Acylation, Adiposity, Appetite, Eating, Exercise, Fasting and Ghrelin.

Author keywords: fullness, gut hormone, hunger and walking.

What This Means in Plain Language

The paper is a randomized study of Ghrelin in 14 individuals.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 2013 (Journal of applied physiology (Bethesda, Md. : 1985)), a journal based in United States.

More context: the Ghrelin compound page, all human trials.