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[Utility of B-type natriuretic peptide measurement in outpatients with heart failure with preserved ejection fraction]

Plain-language guide to PMID 23910641 (2013): observational study study of BNP (Nesiritide).

Key Facts

PMID
23910641
Journal
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
Year
2013
Study type
Observational Study
Authors
Jorge AJ et al. (9 authors)
DOI
10.1016/j.repc.2012.10.019

What This Study Did, in Plain Language

What Was Tested

This observational study paper looks at BNP (Nesiritide).

The aim of this study was to identify the BNP cutoff for a diagnosis of HFPEF in outpatients.

Why It Was Studied

Heart failure with preserved ejection fraction (HFPEF) is a highly prevalent syndrome that is difficult to diagnose in outpatients.

The measurement of B-type natriuretic peptide (BNP) may be useful in the diagnosis of HFPEF, but with a different cutoff from that used in the emergency room.

Who Took Part

By PubMed's age tags, the people studied were older adults, both men and women.

What Was Measured

The measurement of B-type natriuretic peptide (BNP) may be useful in the diagnosis of HFPEF, but with a different cutoff from that used in the emergency room.

Topics PubMed links to this paper include Cross-Sectional Studies, Heart Failure, Natriuretic Peptide, Brain, Outpatients, Reproducibility of Results and Stroke Volume.

Author keywords: B-type natriuretic peptide, Diastole, Diástole, Doentes ambulatórios, Insuficiência cardíaca and Peptídeo natriurético tipo B.

What This Means in Plain Language

This is a observational study of BNP (Nesiritide).

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2013 (Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology), a journal based in Portugal.

More context: the BNP (Nesiritide) compound page, all human trials.

Our Notes on the Compound

BNP (Nesiritide): B-type natriuretic peptide, a 32-amino-acid heart hormone; nesiritide (Natrecor) is a recombinant form used in acute heart failure.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.