Body fat mass is a strong and negative predictor of peak stimulated growth hormone and bone mineral density in healthy adolescents during transition period.

What Was Tested

This clinical trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and GHRH (Growth Hormone-Releasing Hormone).

The adipose tissue has detrimental effects on growth hormone secretion, even in the absence of obesity.

The contribution of body fat mass on growth hormone response to provocative tests during the transition age is not known.

Who Took Part

According to the abstract, 30 adolescents were involved.

By PubMed's age tags, the people studied were teenagers, both men and women.

What Was Measured

The contribution of body fat mass on growth hormone response to provocative tests during the transition age is not known.

The researchers analyzed the GH-IGF1 axis by GHRH-arginine test in 30 healthy adolescents with normal stature during the transition period from 14 to 18 years.

The subject headings attached to it are Absorptiometry, Photon, Adipose Tissue, Adiposity, Arginine, Bone Density, Diagnostic Techniques, Endocrine and Growth Hormone-Releasing Hormone.

What This Means in Plain Language

This is a clinical trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and GHRH (Growth Hormone-Releasing Hormone) in 30 adolescents.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 2013 (Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme), a journal based in Germany.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page and the GHRH (Growth Hormone-Releasing Hormone) compound page, all human trials.