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Associations among dietary zinc intakes and biomarkers of zinc status before and after a zinc supplementation program in Guatemalan schoolchildren.
Plain-language guide to PMID 23964387 (2013): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 23964387
- Journal
- Food and nutrition bulletin
- Year
- 2013
- Study type
- Randomized Controlled Trial
- Authors
- Bui VQ et al. (9 authors)
- DOI
- 10.1177/156482651303400203
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
To assess associations among zinc-related parameters in a sample of Guatemalan school-aged children.
Why It Was Studied
The associations among dietary zinc intakes and biomarkers of zinc status are unknown in apparently healthy children at high risk for zinc deficiency.
Who Took Part
PubMed tags the participants as both men and women.
The researchers assessed total dietary intakes and biomarkers of zinc status before and after receiving 6 months of zinc supplementation or placebo in 691 Guatemalan schoolchildren aged 6 to 11 years.
Most of the children also received zinc-fortified milk from a government program that started shortly after the trial began.
How the Study Was Run
The design is described as randomized, double-blind and placebo-controlled.
The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.
The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.
The researchers assessed associations between zinc intakes and serum zinc, alkaline phosphatase (ALP), and albumin.
What Was Measured
Topics PubMed links to this paper include Alkaline Phosphatase, Biomarkers, Diet, Dietary Supplements, Food, Fortified, Guatemala and Milk.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.
Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2013 (Food and nutrition bulletin), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.