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[Influence of complex deacon-tetra (N1,3-triazole,кN2) copper (II) on the barrier and antioxidant pro people with nasal polyps].
Plain-language guide to PMID 24021824 (2013): controlled clinical trial of Copper (Supplement) in 30 patients.
Key Facts
- PMID
- 24021824
- Journal
- Otolaryngologia polska = The Polish otolaryngology
- Year
- 2013
- Study type
- Controlled Clinical Trial
- Authors
- Malinowska K et al. (4 authors)
- DOI
- 10.1016/j.otpol.2013.02.005
What This Study Did, in Plain Language
What Was Tested
Researchers studied Copper (Supplement) in this controlled clinical trial publication.
The aim of this study was synthesized properties 1,2,4-triazole complex ion Cu (II) to determine their potential antioxidant properties, further indication of activity of antioxidant enzymes: catalase (CAT), glutathione peroxidase (GPX) and superoxide dismutase (Cu-Zn SOD) in patients with nasal polyps and the control group.
Who Took Part
The abstract describes 30 patients taking part.
PubMed indexes the participants as young adults, adults and middle-aged adults, both men and women.
The study was conducted in a group of 30 patients with nasal polyps aged 48±13.50 (test 1 - group with a compound, test 2 - no relation), and 30 in the control group aged 48±17.90 (control 3 - group with a compound, control 4 - no relation).
How the Study Was Run
Blood samples were collected from the antecubital vein into tubes with anticoagulant (heparin sodium).
What Was Measured
Topics PubMed links to this paper include Antioxidants, Catalase, Glutathione Peroxidase, Nasal Polyps, Organometallic Compounds and Superoxide Dismutase.
Author keywords: Complex, Triazole, antyoksydanty, kompleks, polipy nosa and triazol.
What This Means in Plain Language
This is a controlled clinical trial of Copper (Supplement) in 30 patients.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2013 (Otolaryngologia polska = The Polish otolaryngology), a journal based in Poland.
More context: the Copper (Supplement) compound page, all human trials.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.