The role of vitamin D in metabolic disturbances in polycystic ovary syndrome: a systematic review.

What It Covers

Researchers studied Vitamin D, K2, Magnesium and Zinc in this systematic review publication.

The aim of this study was to carry out a systematic review addressing the association between vitamin D status, vitamin D receptor polymorphisms, and/or polymorphisms related to vitamin D metabolism and metabolic disturbances in women with PCOS.

Why It Was Studied

Metabolic disturbances, in particular, insulin resistance (IR) and dyslipidemia, are common in women suffering from polycystic ovary syndrome (PCOS).

Evidence is accumulating that vitamin D status may contribute to the development of metabolic disturbances in PCOS.

Who the Included Studies Covered

PubMed tags the participants as women only.

A systematic search of electronic databases was carried out up to January 2013 for observational studies and clinical trials in women suffering from PCOS with outcome measures that were related to vitamin D status.

How the Review Was Done

The researchers conducted univariate and multivariate regression analyses of the weighted means to gain insights into the association between vitamin D, BMI, and IR based on existing literature.

What Was Measured

Topics PubMed links to this paper include Body Mass Index, Insulin Resistance, Polycystic Ovary Syndrome, Polymorphism, Genetic, Receptors, Calcitriol, Vitamin D and Vitamin D Deficiency.

What This Means in Plain Language

This is a systematic review of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2013 (European journal of endocrinology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.