Needle-free jet injection of rapid-acting insulin improves early postprandial glucose control in patients with diabetes

What Was Tested

This randomized controlled trial paper looks at Insulin Aspart.

Who Took Part

The study group was 12 patients.

By PubMed's age tags, the people studied were young adults, adults, middle-aged adults and older adults, both men and women.

In a randomized, double-blind, double-dummy crossover study, 12 patients with type 1 diabetes and 12 patients with type 2 diabetes received insulin aspart either by jet injection or by conventional pen, in both cases followed by a standardized meal.

How the Study Was Run

In design terms this was a randomized, double-blind and crossover study.

Random assignment meant chance, not the researchers, decided who got Insulin Aspart and who got the comparison, which limits bias.

Blinding on both sides kept the patients and researchers unaware of who received Insulin Aspart.

In the crossover set-up each of the patients took both Insulin Aspart and the comparison in turn, acting as their own control.

What Was Measured

Topics PubMed links to this paper include Blood Glucose, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Hyperglycemia, Hypoglycemic Agents, Injections, Jet and Insulin Aspart.

What This Means in Plain Language

The paper is a randomized, double-blind and crossover study of Insulin Aspart in 12 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2013 (Diabetes care), a journal based in United States.

More context: the Insulin Aspart compound page.