← Human Trials & Peer-Reviewed Studies

Vitamin D levels after UVB radiation: effects by UVA additions in a randomized controlled trial.

Plain-language guide to PMID 24118541 (2013): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
24118541
Journal
Photodermatology, photoimmunology & photomedicine
Year
2013
Study type
Randomized Controlled Trial
Authors
Sallander E et al. (4 authors)
DOI
10.1111/phpp.12076

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

To examine how different combinations of UVA and UVB radiation affect S-25(OH)D for the same vitamin D-weighted exposure.

Why It Was Studied

However, the impact of UVA on vitamin D synthesis by UVB is poorly understood clinically.

Who Took Part

By PubMed's age tags, the people studied were adults, middle-aged adults and older adults, both men and women.

Healthy participants were recruited and subsequently divided into four comparable groups regarding initial 25(OH)D value.

How the Study Was Run

The design is described as randomized.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

The different radiations given were whole-body UVB (n = 23), UVAB (n = 23) and UVA (n = 10).

The controls (n = 19) had no intervention.

Blood samples were collected before the first irradiation (t0), immediately after the last (fifth) irradiation (t1) and then after another 2 days after the last (fifth) irradiation (t2).

What Was Measured

PubMed files the paper under topics including Calcitriol and Ultraviolet Rays.

The authors tagged it with the keywords 25(OH)D, UVA, UVB, sunbeds and vitamin D.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2013 (Photodermatology, photoimmunology & photomedicine), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.