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Factors associated with smoking cessation in early and late pregnancy in the smoking, nicotine, and pregnancy trial: a trial of nicotine replacement therapy.

Plain-language guide to PMID 24127265 (2014): randomized controlled trial of Therapeutic nicotine (patch, non-peptide) in 1,050 women.

Key Facts

PMID
24127265
Journal
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Year
2014
Study type
Randomized Controlled Trial
Authors
Vaz LR et al. (6 authors)
DOI
10.1093/ntr/ntt156

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Therapeutic nicotine (patch, non-peptide), published as a randomized controlled trial.

However, no studies have investigated influences on cessation among women using nicotine replacement therapy (NRT).

Who Took Part

The abstract describes 1,050 women taking part.

By PubMed's age tags, the people studied were young adults and adults, women only.

Data were collected at baseline, 1 month, and delivery from 1,050 pregnant women.

How the Study Was Run

The researchers set it up as a randomized study.

The women were allocated by chance, so the Therapeutic nicotine (patch, non-peptide) group and the comparison group should start out alike.

Two multivariable logistic models for validated cessation at 1 month and delivery were created with a systematic strategy for selection of included factors.

What Was Measured

PubMed files the paper under topics including Cotinine, Logistic Models, Nicotine, Smoking, Smoking Cessation and Tobacco Use Cessation Devices.

What This Means in Plain Language

The paper is a randomized study of Therapeutic nicotine (patch, non-peptide) in 1,050 women.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2014 (Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco), a journal based in England.

More context: the Therapeutic nicotine (patch, non-peptide) compound page, all human trials.

Our Notes on the Compound

Therapeutic nicotine (patch, non-peptide): Pure nicotine as a signaling tool, separated from smoking and vaping.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.