Serum vitamin D level and disease activity in patients with recent onset rheumatoid arthritis.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in the context of rheumatoid arthritis in this observational study publication.

Rheumatoid Arthritis (RA) is one of the most prevalent autoimmune diseases.

Who Took Part

The study group was 66 patients.

PubMed indexes the participants as adults and middle-aged adults, both men and women.

This cross-sectional study was conducted on 66 patients meeting the American College of Rheumatology - European League Against Rheumatism classification criteria for RA.

The disease activity was measured based on Disease Activity Score of 28 joints - erythrocyte sedimentation rate (DAS28-ESR) and serum 25-OH vitamin D (25(OH)D) levels using the chemiluminescent immunoassay method.

How the Study Was Run

It was performed in 2012 using simple sampling.

In addition, the levels of ESR and C-reactive protein (CRP), the duration of morning stiffness, and the number of joints with tenderness and swollen were calculated as well.

The data were analyzed using the Pearson correlation coefficient.

What Was Measured

PubMed files the paper under topics including Arthritis, Rheumatoid, Biomarkers, Blood Sedimentation, Cross-Sectional Studies, Down-Regulation, Health Status Indicators and Immunoassay.

Author keywords: disease activity, rheumatoid arthritis and vitamin D.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc in 66 patients in people with rheumatoid arthritis.

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2016 (International journal of rheumatic diseases), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Rheumatoid arthritis research.