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Multinutrient-fortified juices improve vitamin D and vitamin E status in children: a randomized controlled trial.

Plain-language guide to PMID 24139824 (2014): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 176 children.

Key Facts

PMID
24139824
Journal
Journal of the Academy of Nutrition and Dietetics
Year
2014
Study type
Randomized Controlled Trial
Authors
Economos CD et al. (10 authors)
DOI
10.1016/j.jand.2013.07.027

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Changes in 25(OH)D, α-tocopherol, retinol, and parathyroid hormone concentrations were examined.

Covariates included sex, age, race/ethnicity, body mass index, and baseline 25(OH)D, α-tocopherol, retinol, or parathyroid hormone levels.

Who Took Part

According to the abstract, 176 children were involved.

By PubMed's age tags, the people studied were children, both men and women.

One hundred eighty participants (aged 8.04±1.42 years) were recruited at Tufts (n=70) and Boston University (n=110) during 2005-2006.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

A 12-week randomized, double-blind, controlled trial.

What Was Measured

Covariates included sex, age, race/ethnicity, body mass index, and baseline 25(OH)D, α-tocopherol, retinol, or parathyroid hormone levels.

Multivariate models and repeated measures analysis of variance tested for group differences with pre-post measures (n=141).

The subject headings attached to it are Beverages, Body Mass Index, Boston, Calcium, Dietary, Citrus sinensis, Food, Fortified and Multivariate Analysis.

The authors tagged it with the keywords Multinutrient juice, Vitamin D and Vitamin E.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 176 children.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2014 (Journal of the Academy of Nutrition and Dietetics), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.