← Human Trials & Peer-Reviewed Studies
Vitamin D improves endometrial thickness in PCOS women who need intrauterine insemination: a randomized double-blind placebo-controlled trial.
Plain-language guide to PMID 24158736 (2014): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 110 patients, endometriosis.
Key Facts
- PMID
- 24158736
- Journal
- Archives of gynecology and obstetrics
- Year
- 2014
- Study type
- Randomized Controlled Trial
- Authors
- Asadi M et al. (6 authors)
- DOI
- 10.1007/s00404-013-3055-x
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc in the context of endometriosis and pcos.
To determine whether administration of vitamin D affects the success rates of intra uterine insemination (IUI) in infertile polycystic ovarian syndrome (PCOS) women and their endometrial thickness.
Who Took Part
According to the abstract, 110 patients were involved.
PubMed indexes the participants as adults, women only.
This randomized, double-blind, placebo-controlled trial was conducted in an infertility clinic of Women's Hospital, and 110 infertile PCOS patients undergoing IUI were randomly divided to receive vitamin D or placebo.
How the Study Was Run
The researchers set it up as a randomized, double-blind and placebo-controlled study.
The patients were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.
The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.
What Was Measured
PubMed files the paper under topics including Endometrium, Infertility, Female, Insemination, Artificial, Ovarian Follicle, Polycystic Ovary Syndrome, Pregnancy Rate and Ultrasonography.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 110 patients in people with endometriosis.
Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2014 (Archives of gynecology and obstetrics), a journal based in Germany.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, Endometriosis research, PCOS research.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.