The effects of low vitamin D on coronary artery disease.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Coronary Artery Disease (CAD) remains a major cause of morbidity and mortality in the world.

The researchers planned to research the association between low vitamin D status and the severity of CAD.

Why It Was Studied

The data presented are the mean levels/values and standard deviation.

Who Took Part

The study group was 348 patients.

By PubMed's age tags, the people studied were middle-aged adults and older adults, both men and women.

A total of 348 consecutive patients undergoing coronary angiography for evaluation of CAD were included in this study. 25-Hydroxyvitamin D [25(OH)D] was measured by chemiluminescence assay.

How the Study Was Run

The researchers set it up as a randomized study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

CAD severity was assessed by using the SYNTAX scores.

What Was Measured

The data presented are the mean levels/values and standard deviation.

The subject headings attached to it are Coronary Artery Disease, Coronary Stenosis and Vitamin D.

Author keywords: Coronary angiography, Inflammation and SYNTAX scores.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 348 patients.

With several hundred people or more, it is a fairly large study for this kind of research.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2014 (Heart, lung & circulation), a journal based in Australia.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.