Effect of calcium-vitamin D supplementation on metabolic profiles in pregnant women at risk for pre-eclampsia: a randomized placebo-controlled trial.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

This study was designed to determine the effects of consumption calcium-vitamin D supplements on metabolic profiles among Iranian pregnant women at risk for pre-eclampsia.

Why It Was Studied

To their knowledge, no reports are available indicating the effects of calcium-vitamin D supplementation on metabolic profiles among pregnant women at risk for pre-eclampsia.

This randomized single-blind controlled clinical trial was performed among 49 pregnant women at risk for pre-eclampsia, primigravida, aged 18-35 year old who were carrying singleton pregnancy at their third trimester.

Who Took Part

The study group was 49 women.

PubMed indexes the participants as teenagers, young adults and adults, women only.

How the Study Was Run

The researchers set it up as a randomized, single-blind and placebo-controlled study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

In this single-blind Vitamin D, K2, Magnesium and Zinc study one party knew the assignments and the other did not.

Some women received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

What Was Measured

The subject headings attached to it are Biomarkers, Blood Glucose, Calcium Carbonate, Cholecalciferol, Cholesterol, Cholesterol, HDL and Cholesterol, LDL.

What This Means in Plain Language

The paper is a randomized, single-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 49 women.

The publication is from 2012 (Pakistan journal of biological sciences : PJBS), a journal based in Pakistan.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.