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Effects of zinc supplementation on serum zinc and leptin levels, BMI, and body composition in hemodialysis patients.
Plain-language guide to PMID 24188897 (2014): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 24188897
- Journal
- Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
- Year
- 2014
- Study type
- Randomized Controlled Trial
- Authors
- Argani H et al. (6 authors)
- DOI
- 10.1016/j.jtemb.2013.09.001
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
The aim of this study was to determine the effects of zinc supplementation on serum zinc and leptin levels as well as on anthropometric status and some biochemical parameters in hemodialysis (HD) patients.
Why It Was Studied
Anthropometric measurements were taken using standard calibrated instruments.
Serum zinc and leptin levels were determined by atomic absorption and ELISA method respectively before and after intervention.
Who Took Part
By PubMed's age tags, the people studied were middle-aged adults.
How the Study Was Run
The design is described as randomized, double-blind and placebo-controlled.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.
Some participants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.
What Was Measured
Anthropometric measurements were taken using standard calibrated instruments.
Serum zinc and leptin levels were determined by atomic absorption and ELISA method respectively before and after intervention.
Topics PubMed links to this paper include Body Composition, Body Mass Index, Dietary Supplements, Leptin, Renal Dialysis and Zinc.
The authors tagged it with the keywords BMI, Hemodialysis, Serum leptin and Serum zinc.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.
Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2014 (Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)), a journal based in Germany.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.