Assessment of endometrial receptivity using Doppler ultrasonography in infertile women undergoing intrauterine insemination

What Was Tested

The paper reports a study of hCG (human chorionic gonadotropin) in the context of endometriosis, published as a randomized controlled trial.

The aim of this study was assessment of subendometrial blood flow with Doppler ultrasonography as an indicator of endometrial receptivity in stimulated cycles for intrauterine insemination (IUI).

Who Took Part

According to the abstract, 90 women were involved.

By PubMed's age tags, the people studied were adults, women only.

This prospective study enrolled 90 women scheduled for IUI after ovarian stimulation randomly assigned to one of the three equal groups; group (C) received Clomiphene citrate, group (H) received HMG and group (CH) received Clomiphene citrate in addition to HMG.

All participants had ultrasound folliculometry starting on day 9, followed by transvaginal Doppler study of the subendometrial blood flow and perifollicular blood flow on the day of detecting at least one follicle >18 mm.

How the Study Was Run

The design is described as randomized.

Random assignment meant chance, not the researchers, decided who got hCG (human chorionic gonadotropin) and who got the comparison, which limits bias.

Resistivity index (RI) and pulsatility index (PI) of subendometrial and perifollicular flow were measured.

Endometrial thickness was measured on day of hCG injection.

What Was Measured

The subject headings attached to it are Chorionic Gonadotropin, Embryo Implantation, Endometrium, Infertility, Female, Insemination, Artificial, Organ Size and Pregnancy Rate.

What This Means in Plain Language

The paper is a randomized study of hCG (human chorionic gonadotropin) in 90 women in people with endometriosis.

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2014 (Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology), a journal based in England.

More context: the hCG (human chorionic gonadotropin) compound page, Endometriosis research.