Postoperative PTH measurement is not a reliable predictor for hypocalcemia after total thyroidectomy in vitamin D deficiency: prospective study of 203 cases.

What Was Tested

This clinical trial looks at Vitamin D, K2, Magnesium and Zinc.

The aim of the present study was to evaluate the accuracy of PTH as a predictor of post-TT hypocalcemia in patients with vitamin D deficiency.

Why It Was Studied

Several factors have been used to predict post total thyroidectomy (TT) hypocalcemia.

Serum intact PTH (PTH) levels <10 pg/mL after TT is considered to be the most accurate predictor.

Who Took Part

The abstract describes 2011 patients taking part.

PubMed indexes the participants as adults and middle-aged adults, both men and women.

The present prospective study was conducted from 2009 to 2011 and included patients undergoing TT for benign goiter.

The PTH levels 8 h after TT in patients who were vitamin D sufficient (group A; S Vit D >20 ng/mL) versus those who were vitamin D deficient (group B) were compared.

How the Study Was Run

Comparison was also performed between patients belonging to group A and group B who developed hypocalcemia.

Appropriate statistical tests were applied.

What Was Measured

Serum intact PTH (PTH) levels <10 pg/mL after TT is considered to be the most accurate predictor.

Topics PubMed links to this paper include Biomarkers, Goiter, Hypocalcemia, Parathyroid Hormone, Postoperative Care, Postoperative Complications and Postoperative Period.

What This Means in Plain Language

This is a clinical trial of Vitamin D, K2, Magnesium and Zinc in 2011 patients.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2014 (World journal of surgery), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.