← Human Trials & Peer-Reviewed Studies
The association between drugs frequently used by the elderly and vitamin D blood levels: a review of observational and experimental studies.
Plain-language guide to PMID 24385337 (2014): review of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 24385337
- Journal
- Drugs & aging
- Year
- 2014
- Study type
- Review
- Authors
- van Orten-Luiten AC et al. (4 authors)
- DOI
- 10.1007/s40266-013-0137-1
What This Paper Covers, in Plain Language
What It Covers
This review looks at Vitamin D, K2, Magnesium and Zinc.
As the prevalence of vitamin D deficiency in the elderly is high, the primary objective of this review is to evaluate the literature on the relationship between drug use and vitamin D status, focusing on medicines commonly used by the elderly.
Why It Was Studied
In the field of ADRs, drug-nutrient interactions (DNIs) are a relatively unexplored area.
PubMed was searched for human epidemiological and clinical studies published until early 2013, investigating the relationship between vitamin D blood levels and use of drugs from one of the following groups: proton pump inhibitors (PPIs), biguanides, vitamin K antagonists, platelet aggregation inhibitors, thiazide diuretics, loop diuretics, beta-blocking agents, calcium channel blockers, angiotensin-converting enzyme (ACE) inhibitors, angiotensin-II antagonists, statins, benzodiazepines, and antidepressants.
Who the Included Studies Covered
The age groups tagged for this paper are middle-aged adults and older adults.
What Was Measured
PubMed was searched for human epidemiological and clinical studies published until early 2013, investigating the relationship between vitamin D blood levels and use of drugs from one of the following groups: proton pump inhibitors (PPIs), biguanides, vitamin K antagonists, platelet aggregation inhibitors, thiazide diuretics, loop diuretics, beta-blocking agents, calcium channel blockers, angiotensin-converting enzyme (ACE) inhibitors, angiotensin-II antagonists, statins, benzodiazepines, and antidepressants.
PubMed files the paper under topics including Angiotensin-Converting Enzyme Inhibitors, Antidepressive Agents, Calcium Channel Blockers, Diuretics, Drug-Related Side Effects and Adverse Reactions, Nutritional Status and Observational Studies as Topic.
What This Means in Plain Language
This is a review of Vitamin D, K2, Magnesium and Zinc.
The publication is from 2014 (Drugs & aging), a journal based in New Zealand.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.