The association of serum 25-OH vitamin D with atopy, asthma, and lung function in a prospective study of Danish adults.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a clinical trial.

The purpose of this study was to investigate associations of serum levels of 25-hydroxy vitamin D (25(OH)D) with atopy, asthma, and lung function in a prospective study of Danish adults.

Who Took Part

The abstract describes 4999 adults taking part.

PubMed indexes the participants as adults and middle-aged adults, both men and women.

This study included 4999 adults aged 30-60 years in 1999-2001.

No information on use of vitamin D supplements was available.

How the Study Was Run

Three thousand and thirty-two of those included at baseline also participated at a follow-up examination 5 years later, and 3727 answered a 10-year follow-up questionnaire.

Serum levels of (25(OH)D) were measured by high-performance liquid chromatography (HPLC) at baseline.

Specific IgE against four common antigens was measured.

Information about doctor-diagnosed asthma was obtained from questionnaires, and lung function (FEV1 and forced vital capacity) was measured by spirometry.

What Was Measured

Topics PubMed links to this paper include Asthma, Calcifediol and Respiratory Function Tests.

The authors tagged it with the keywords adults, atopy, epidemiology, lung function and vitamin D.

What This Means in Plain Language

This is a clinical trial of Vitamin D, K2, Magnesium and Zinc in 4999 adults.

With several hundred people or more, it is a fairly large study for this kind of research.

The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2015 (Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.