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Calcium supplementation and parathyroid hormone response to vigorous walking in postmenopausal women

Plain-language guide to PMID 24576866 (2014): double-blind randomized controlled trial study of Parathyroid Hormone (PTH 1-84) in 1, women.

Key Facts

PMID
24576866
Journal
Medicine and science in sports and exercise
Year
2014
Study type
Randomized Controlled Trial
Authors
Shea KL et al. (6 authors)
DOI
10.1249/MSS.0000000000000320

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial paper looks at Parathyroid Hormone (PTH 1-84).

Disruptions in calcium (Ca) homeostasis during exercise may influence skeletal adaptations to exercise training.

Who Took Part

The abstract describes 1, women taking part.

The age groups tagged for this paper are middle-aged adults and older adults, women only.

How the Study Was Run

In design terms this was a randomized, double-blind and crossover study.

The women were allocated by chance, so the Parathyroid Hormone (PTH 1-84) group and the comparison group should start out alike.

Neither the women nor the staff measuring them knew who was on Parathyroid Hormone (PTH 1-84), so expectations could not easily colour the readings.

In the crossover set-up each of the women took both Parathyroid Hormone (PTH 1-84) and the comparison in turn, acting as their own control.

What Was Measured

PubMed files the paper under topics including Bone Resorption, Calcium, Dietary, Collagen Type I, Dietary Supplements, Homeostasis, Parathyroid Hormone and Peptides.

What This Means in Plain Language

The paper is a randomized, double-blind and crossover study of Parathyroid Hormone (PTH 1-84) in 1, women.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2014 (Medicine and science in sports and exercise), a journal based in United States.

More context: the Parathyroid Hormone (PTH 1-84) compound page, all human trials.

Our Notes on the Compound

Parathyroid Hormone (PTH 1-84): The 84-amino-acid hormone that raises blood calcium; full-length PTH (Natpara) has been used in hypoparathyroidism. Teriparatide is its 1-34 fragment.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.