← Human Trials & Peer-Reviewed Studies

Effect of oxytocin discontinuation during the active phase of labor

Plain-language guide to PMID 24646336 (2015): randomized controlled trial study of Oxytocin in 140 patients.

Key Facts

PMID
24646336
Journal
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Year
2015
Study type
Randomized Controlled Trial
Authors
Öztürk FH et al. (4 authors)
DOI
10.3109/14767058.2014.906573

What This Study Did, in Plain Language

What Was Tested

Researchers studied Oxytocin in this randomized controlled trial publication.

To observe the progression of labor when oxytocin use is limited to the onset of the active stage of labor.

Who Took Part

The abstract describes 140 patients taking part.

The age groups tagged for this paper are young adults and adults, women only.

A randomized, prospective controlled study was performed to address the issue of oxytocin infusion after the onset of active labor in 140 patients.

In the control group, incremental oxytocin infusion was administered until 5 cm cervical dilatation, and then was maintained at the same level until delivery.

How the Study Was Run

The design is described as randomized.

The patients were allocated by chance, so the Oxytocin group and the comparison group should start out alike.

In the study group, infusion of oxytocin was discontinued at the onset of the active phase of labor, which was accepted as a cervical dilatation of 5 cm.

What Was Measured

PubMed files the paper under topics including Cesarean Section, Delivery, Obstetric, Labor Onset, Labor Stage, First, Labor, Induced, Oxytocin and Pregnancy Outcome.

Author keywords: Active phase of labor and desensitization.

What This Means in Plain Language

The paper is a randomized study of Oxytocin in 140 patients.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2015 (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians), a journal based in England.

More context: the Oxytocin compound page, all human trials.

Our Notes on the Compound

Oxytocin: A peptide hormone with established obstetric medical uses and a less settled role in research on behavior, sexual function and appetite.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.