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The influence of age and exercise modality on growth hormone bioactivity in women.

Plain-language guide to PMID 24786514 (2015): crossover randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Key Facts

PMID
24786514
Journal
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
Year
2015
Study type
Randomized Controlled Trial
Authors
Gordon SE et al. (6 authors)
DOI
10.1016/j.ghir.2014.03.005

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Prior research has indicated that the loss of skeletal muscle mass and bone mineral density observed with aging is related to the prominent age-related decline in the concentration of serum growth hormone (GH).

However, there is limited data on the effects of aging on GH responses to acute bouts of heavy resistance exercise (HRE) and aerobic exercise (AE).

Who Took Part

PubMed indexes the participants as young adults, adults and middle-aged adults, women only.

The present investigation examined the effects of a HRE protocol and an AE protocol on immunoreactive GH (IGH) and bioactive GH (BGH) in active young and old women.

How the Study Was Run

The researchers set it up as a randomized and crossover study.

The participants were allocated by chance, so the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group should start out alike.

Each person switched between Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and the comparison at some point, usually with a gap in between.

What Was Measured

PubMed files the paper under topics including Age Factors, Aging, Exercise, Exercise Test, Human Growth Hormone, Recovery of Function and Resistance Training.

Author keywords: Bioassay, Immunoreactivity assays, Rat tibial line assay and Resistance exercise.

What This Means in Plain Language

The paper is a randomized and crossover study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2015 (Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society), a journal based in Scotland.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.