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Effects of exercise in the cold on Ghrelin, PYY, and food intake in overweight adults
Plain-language guide to PMID 24870575 (2015): randomized controlled trial study of Ghrelin in 10 men.
Key Facts
- PMID
- 24870575
- Journal
- Medicine and science in sports and exercise
- Year
- 2015
- Study type
- Randomized Controlled Trial
- Authors
- Crabtree DR et al. (2 authors)
- DOI
- 10.1249/MSS.0000000000000391
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Ghrelin, published as a randomized controlled trial.
However, the effect of cold exercise on EI in overweight individuals has yet to be examined.
The present study investigated the effect of brisk walking in a cold (8°C) and neutral (20°C) environment on postexercise EI and appetite hormone responses.
Who Took Part
According to the abstract, 10 men were involved.
The age groups tagged for this paper are adults and middle-aged adults, both men and women.
Sixteen overweight participants (10 men and six women; age, 50.1 ± 11.6 yr; body mass index, 28.9 ± 4.2 kg·m) completed a 45-min treadmill walk at 8°C and 20°C in a randomized counterbalanced design.
Participants were presented with an ad libitum buffet meal 45 min after exercise, and EI was covertly measured.
How the Study Was Run
The researchers set it up as a randomized study.
Random assignment meant chance, not the researchers, decided who got Ghrelin and who got the comparison, which limits bias.
Skin and rectal temperature were monitored throughout exercise and for 30 min after exercise, and concentrations of the appetite hormones total ghrelin, acylated ghrelin, and total peptide YY were assessed before and after exercise and before and after meal.
What Was Measured
PubMed files the paper under topics including Acylation, Cold Temperature, Eating, Energy Intake, Ghrelin, Overweight and Peptide YY.
What This Means in Plain Language
The paper is a randomized study of Ghrelin in 10 men.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2015 (Medicine and science in sports and exercise), a journal based in United States.
More context: the Ghrelin compound page, all human trials.
Our Notes on the Compound
Ghrelin: A 28-amino-acid stomach hormone that signals hunger and triggers growth hormone release; studied in human trials as an infusion.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.