Effects of calcium-vitamin D co-supplementation on metabolic profiles in vitamin D insufficient people with type 2 diabetes: a randomised controlled clinical trial.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

This study was performed to assess the effects of vitamin D and calcium supplementation on the metabolic profiles of vitamin D insufficient persons with type 2 diabetes.

Why It Was Studied

ClinicalTrials.gov NCT01662193 FUNDING: Clinical Research Council, Isfahan University of Medical Sciences, Isfahan, Iran.

Who Took Part

The age groups tagged for this paper are middle-aged adults, both men and women.

In a parallel designed randomised placebo-controlled clinical trial, a total of 118 non-smoker individuals with type 2 diabetes and insufficient 25-hydroxyvitamin D, aged >30 years, were recruited from the Isfahan Endocrine and Metabolism Research Centre.

All investigators, participants and laboratory technicians were blinded to the random assignments.

How the Study Was Run

The design is described as randomized, placebo-controlled and parallel-group.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Some participants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

The Vitamin D, K2, Magnesium and Zinc group and the comparison group ran side by side rather than switching.

A study technician carried out the random allocations using a random numbers table.

All participants provided 3 days of dietary records and 3 days of physical activity records throughout the intervention.

What Was Measured

PubMed files the paper under topics including Blood Glucose, Calcium, Diabetes Mellitus, Type 2, Dietary Supplements, Vitamin D and Vitamin D Deficiency.

What This Means in Plain Language

The paper is a randomized, placebo-controlled and parallel-group study of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2014 (Diabetologia), a journal based in Germany.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.