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Complementary treatment of obesity and overweight with salacia reticulata and vitamin d.
Plain-language guide to PMID 25008011 (2013): open-label randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 40 participants.
Key Facts
- PMID
- 25008011
- Journal
- International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition
- Year
- 2013
- Study type
- Randomized Controlled Trial
- Authors
- Ofner M et al. (4 authors)
- DOI
- 10.1024/0300-9831/a000162
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.
Their goal was to determine its potential effect for humans with obesity.
Why It Was Studied
The Indian plant root Salacia reticulata, which is rich in alpha-glucosidase inhibitors, is used for metabolic disorders in Ayurvedic medicine.
Vitamin D₃ is also used in the treatment of some metabolic diseases.
Who Took Part
According to the abstract, 40 participants were involved.
PubMed indexes the participants as adults and middle-aged adults, both men and women.
In a randomized open-label study, the researchers investigated 40 healthy participants aged 30 - 60 years, physically active, with a body mass index (BMI) of 25 - 45.
The participants were randomly allocated into two groups.
How the Study Was Run
The design is described as randomized and open-label.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
Being open-label, the Vitamin D, K2, Magnesium and Zinc study did not mask who received what.
Body weight, BMI, and body composition were measured.
What Was Measured
PubMed files the paper under topics including Body Composition, Body Mass Index, Exercise, Life Style, Obesity, Overweight and Plant Extracts.
Author keywords: Salacia reticulata, exadipin, lifestyle, training and vitamin D.
What This Means in Plain Language
The paper is a randomized and open-label study of Vitamin D, K2, Magnesium and Zinc in 40 participants.
Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2013 (International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition), a journal based in Singapore.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.