The effects of vitamin D supplementation on airway functions in mild to moderate persistent asthma.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

To explore the synergistic effects of vitamin D supplementation in addition to asthma controllers (ICS or ICS plus long-acting β-agonist) on airway functions.

Who Took Part

According to the abstract, 130 individuals were involved.

By PubMed's age tags, the people studied were children, teenagers, young adults, adults and middle-aged adults, both men and women.

Spirometric parameters (forced expiratory volume in 1 second [FEV1] and ratio of FEV1 to forced vital capacity) and serum vitamin D measurement were obtained before and 8 and 24 weeks after the intervention.

Patients were divided in 2 groups randomly.

How the Study Was Run

In design terms this was a randomized study.

The individuals were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Data on age, sex, body mass index, stage of asthma, serum total IgE, history of allergic rhinitis, atopic dermatitis, food allergy, and urticaria were collected.

What Was Measured

PubMed files the paper under topics including Anti-Inflammatory Agents, Asthma, Bronchodilator Agents, Budesonide, Dermatitis, Atopic, Dietary Supplements and Drug Synergism.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 130 individuals.

Its findings take up roughly 2 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2014 (Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.