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Prospective randomized trial of oxytocin administration for active management of the third stage of labor
Plain-language guide to PMID 25108586 (2014): randomized controlled trial study of Oxytocin.
Key Facts
- PMID
- 25108586
- Journal
- International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
- Year
- 2014
- Study type
- Randomized Controlled Trial
- Authors
- Oguz Orhan E et al. (5 authors)
- DOI
- 10.1016/j.ijgo.2014.05.022
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial paper looks at Oxytocin.
To determine the most efficient route and timing of oxytocin administration for active management of the third stage of labor.
Who Took Part
The age groups tagged for this paper are young adults and adults, women only.
Women with a singleton pregnancy (>37 weeks) who had a live vaginal birth were randomly allocated to four groups: iv-A (intravenous oxytocin after delivery of the fetus), iv-B (when anterior shoulder seen), im-A (intramuscular oxytocin after delivery), and im-B (when anterior shoulder seen).
How the Study Was Run
The researchers set it up as a randomized study.
Random assignment meant chance, not the researchers, decided who got Oxytocin and who got the comparison, which limits bias.
A prospective randomized study was done at one center in Ankara, Turkey, between January and October 2010.
Postpartum blood loss within the first hour, hemoglobin, hematocrit, and duration of the third stage were compared.
What Was Measured
PubMed files the paper under topics including Labor Stage, Third, Oxytocics, Oxytocin and Postpartum Hemorrhage.
Author keywords: Active management of third stage of labor and Labor augmentation.
What This Means in Plain Language
The paper is a randomized study of Oxytocin.
Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2014 (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics), a journal based in United States.
More context: the Oxytocin compound page, all human trials.
Our Notes on the Compound
Oxytocin: A peptide hormone with established obstetric medical uses and a less settled role in research on behavior, sexual function and appetite.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.