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Calcium-vitamin D cosupplementation influences circulating inflammatory biomarkers and adipocytokines in vitamin D-insufficient diabetics: a randomized controlled clinical trial.
Plain-language guide to PMID 25215557 (2014): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 118 patients.
Key Facts
- PMID
- 25215557
- Journal
- The Journal of clinical endocrinology and metabolism
- Year
- 2014
- Study type
- Randomized Controlled Trial
- Authors
- Tabesh M et al. (5 authors)
- DOI
- 10.1210/jc.2014-1977
- Registered trial
- NCT01662193
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
This study was performed to assess the effects of vitamin D and calcium supplementation on inflammatory biomarkers and adipocytokines in vitamin D-insufficient people with type 2 diabetes.
Why It Was Studied
To the best of their knowledge, no study has examined the effects of vitamin D-calcium cosupplementation on inflammatory biomarkers and adipocytokines in vitamin D-insufficient type 2 diabetics.
Who Took Part
The study group was 118 patients.
By PubMed's age tags, the people studied were middle-aged adults and older adults, both men and women.
Totally, 118 diabetic patients were enrolled in this randomized, placebo-controlled clinical trial.
How the Study Was Run
The researchers set it up as a randomized, double-blind and placebo-controlled study.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
Blinding on both sides kept the patients and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.
A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.
What Was Measured
PubMed files the paper under topics including Adipokines, Biomarkers, C-Reactive Protein, Calcium, Dietary, Diabetes Mellitus, Type 2, Dietary Supplements and Inflammation.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 118 patients.
Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2014 (The Journal of clinical endocrinology and metabolism), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.