Recombinant human growth hormone for treating burns and donor sites.

What It Covers

Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in this meta-analysis publication.

To determine the effects of rhGH on the healing rate of burn wounds and donor sites in people with burns.

Why It Was Studied

This change in protein metabolism correlates with poor wound healing of the burn and donor sites.

Randomised controlled trials (RCTs) comparing rhGH with any comparator intervention, e.g. oxandrolone or placebo, in adults or children with burns.

Who the Included Studies Covered

PubMed indexes the participants as infants, young children, children, teenagers, young adults, adults, middle-aged adults and older adults.

How the Review Was Done

For this first update the researchers searched the Cochrane Wounds Group Specialised Register (searched 04 September 2014); The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2014, Issue 8); Database of Abstracts of Reviews of Effects (DARE) (The Cochrane Library 2014, Issue 3); Ovid MEDLINE (1950 to September Week 4 2014); Ovid MEDLINE (In-Process & Other Non-Indexed Citations September 8, 2014); Ovid EMBASE (1980 to 2014 Week 35); and EBSCO CINAHL (1982 to 8 September 2014).

What Was Measured

Two review authors independently selected studies, assessed trial quality and extracted data.

The primary outcomes were the healing of the burn wound and donor sites and the occurrence of wound infections.

The subject headings attached to it are Anabolic Agents, Body Surface Area, Burns, Human Growth Hormone, Oxandrolone, Randomized Controlled Trials as Topic and Recombinant Proteins.

What This Means in Plain Language

This is a meta-analysis of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

The abstract goes on to report its results in about 12 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2014 (The Cochrane database of systematic reviews), a journal based in England.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.