Midlife dietary vitamin D intake and subsequent performance in different cognitive domains.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The researchers evaluated the cross-time association between midlife dietary vitamin D intake and subsequent cognitive performance in a French general-population sample.

Who Took Part

The age groups tagged for this paper are adults and middle-aged adults, both men and women.

Data from participants in both the SU.VI.MAX trial (1994-2002) and the SU.VI.MAX 2 observational study (2007-2009) were used.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

Dietary intake was estimated at baseline from 6 or more 24-hour records.

Cognitive performance was evaluated 13 years later with a comprehensive neuropsychological battery.

Parameter estimates of cognitive performance according to quartiles (Q) of vitamin D intake were estimated via ANCOVA.

What Was Measured

Topics PubMed links to this paper include Aging, Alcohol Drinking, Cognition, Cognition Disorders, Diet, Dietary Carbohydrates and Dietary Fats.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2014 (Annals of nutrition & metabolism), a journal based in Switzerland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.