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Lower vitamin D status in obese compared with normal-weight women despite higher vitamin D intake in early pregnancy.

Plain-language guide to PMID 25307530 (2015): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).

Key Facts

PMID
25307530
Journal
Clinical nutrition (Edinburgh, Scotland)
Year
2015
Study type
Randomized Controlled Trial
Authors
Karlsson T et al. (9 authors)
DOI
10.1016/j.clnu.2014.09.012

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in this randomized controlled trial publication.

The purpose of this study was to compare vitamin D status and intake between obese and normal-weight women during pregnancy.

Why It Was Studied

Pregnancy may affect vitamin D status, especially in obese subjects.

Who Took Part

PubMed tags the participants as women only.

Twenty-five obese and 80 normal-weight women were recruited in the Western Sweden region (latitude 57°N).

How the Study Was Run

In design terms this was a randomized study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Blood samples and information on diet and sun exposure were collected in each trimester during pregnancy.

What Was Measured

PubMed files the paper under topics including Body Composition, Body Mass Index, Diet, Dietary Supplements, Energy Intake, Maternal Nutritional Physiological Phenomena and Obesity.

Author keywords: 25(OH)D, Pregnancy, Supplement use, Vitamin D intake and Vitamin D status.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2015 (Clinical nutrition (Edinburgh, Scotland)), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.

Our Notes on the Compounds

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.