Higher vitamin D serum concentration increases health related quality of life in patients with inflammatory bowel diseases.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as an observational study.

To investigate the effect of vitamin D (VD) concentrations and VD supplementation on health related quality of life in inflammatory bowel disease (IBD) patients.

Who Took Part

According to the abstract, 220 patients were involved.

The age groups tagged for this paper are adults and middle-aged adults, both men and women.

A cohort of 220 IBD patients including 141 Crohn's disease (CD) and 79 ulcerative colitis (UC) patients was followed-up at a tertiary IBD center.

A subgroup of the cohort (n = 26) took VD supplements for > 3 mo.

How the Study Was Run

Health related quality of life was assessed using the short IBD questionnaire (sIBDQ).

VD serum concentration and sIBDQ score were assessed between August and October 2012 (summer/autumn period) and between February and April 2013 (winter/spring period).

The mean VD serum concentration and its correlation with disease activity of CD were determined for each season separately.

In a subgroup of patients, the effects of VD supplementation on winter VD serum concentration, change in VD serum concentration from summer to winter, and winter sIBDQ score were analyzed.

What Was Measured

Topics PubMed links to this paper include Biomarkers, Calcifediol, Colitis, Ulcerative, Crohn Disease, Dietary Supplements, Prevalence and Quality of Life.

The authors tagged it with the keywords Crohn’s disease, Health related quality of life, Ulcerative colitis, Vitamin D and Vitamin D supplementation.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc in 220 patients.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2014 (World journal of gastroenterology), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.